Neuroimaging for Stroke Diagnosis

In animal stroke models, especially in large animal models of stroke studies, neuroimaging is well suited to monitor changes in the brain after a stroke, which provides great convenience in exploring stroke pathological processes and designing stroke treatment plans. With this in mind, Ace Therapeutics offers comprehensive services for neuroimaging techniques used in stroke. Based on state-of-the-art equipment, our scientists facilitate your stroke research through high-quality services and professional technologies. Also, related research has also facilitated the use of neuroimaging-based stroke diagnostics for humans.

Determination of The Infarct Core for Stroke

Ischemic parenchyma, also known as the infarct core, is caused by irreversible damage due to inadequate perfusion. Identification of the infarct core is the main reference for guiding subsequent treatment. Ace Therapeutics initially defines the infarct core in ischemic stroke by the combination of computed tomography (CT), diffusion-weighted imaging (DWI), and magnetic resonance imaging (MRI).

Penumbra Imaging Technology for Stroke

The ischemic penumbra, also known as "tissue - at - risk", is the severely hypoperfused parenchyma that suffers from neuronal silencing and therefore also leads to neurological deficits. However, if timely protective measures are taken in the penumbra region, the damage caused by a stroke can be reversed and the damage caused by a stroke to the brain can be reduced, which makes it possible to develop stroke therapies based on neuroprotection. With this in mind, Ace Therapeutics offers comprehensive services to image the post-stroke penumbra region. We image the post-stroke brain by CT perfusion imaging or MR perfusion imaging techniques to distinguish the core infarct area from the penumbra and surrounding benign oligemia areas.

Arterial Imaging Technology for Stroke

The implementation of arterial imaging techniques allows for some understanding of cerebrovascular damage during stroke pathology and thus an adequate assessment of the physiological and pathological process of stroke. Therefore, Ace Therapeutics provides a comprehensive and high-quality service for the monitoring of arteries in stroke pathology and the development of arterial-based stroke therapies.

• We image the arterial lumen by CT angiography or MR angiography. We provide " lumenography " through combined intracranial and extracranial carotid assessment.
• We visualize and monitor the mural hematoma in cases of arterial dissection with fat-suppressed T1 - weighted MRI imaging.
• We detect the dissection membrane by contrast-enhanced CT angiography and MR angiography.
• We predict infarct hemorrhagic transformation by MRI with fluid-attenuated inversion recovery sequence-MRI to observe the hyperintensity of the CSF space on FLAIR - MRI or parenchymal enhancement after intravenous administration of gadolinium

If you would like to learn more about our services, please feel free to contact us.

1. El-Koussy, M., et al., Imaging of acute ischemic stroke. Eur Neurol, 2014. 72(5-6): p. 309-316.