Development of Small Molecule Drug for Stroke

While the rise of biologics has enriched the types of drugs and improved cure rates, small molecule drugs have always been an important area of drug development. Ace Neuroscience offers comprehensive services for the development of small molecule drugs for stroke therapy. We provide professional and comprehensive services for drug screening, drug efficacy testing, pharmacokinetic testing, safety evaluation testing, and pharmaceutic preparations. Our comprehensive services are designed to facilitate the smooth conduct of your research.

Targeted Stroke Drug Development

Targeted Stroke Drug Development

For different targets, Ace Neuroscience offers different services according to their specific mechanisms of action.

Stroke Drug Development Targeting Cell Death

Stroke Drug Development Targeting Cell Death

Cell death is one of the important pathways in the elaboration of the pathological processes it undergoes, and is an important target in the regulation of stroke pathology. In view of this, Ace Neuroscience offers a comprehensive service to develop stroke drugs for different cell death types.

  • Given the role of iron metabolism, lipid peroxidation metabolism, and amino acid metabolism in ferroptosis, we offer a specialized drug screening service to screen for modulators targeting these pathways with potential therapeutic effects in stroke.
  • Given the role of inflammation in pyroptosis, we perform high throughput screening for inhibitors targeting inflammatory pathways associated with pyroptosis with the aim of obtaining drugs with potential therapeutic activity in stroke.
  • Necroptosis is a specific type of programmed cell death. Given the important role of RIP1, RIP3, and MLKL in necroptosis, we conducted a comprehensive screening for regulators of RIP1, RIP3, and MLKL-related signaling pathways in stroke pathology with the aim of obtaining drugs with potential therapeutic activity in stroke.

Stroke Drug Development Targeting Different Cell Types

Stroke Drug Development Targeting Different Cell Types

Different cell types, especially brain cells, can mimic the pathology of the post-stroke brain to some extent. At the same time, the different roles of brain cells are targeted to screen for appropriate modulators to obtain drug candidates with potential stroke therapeutic effects. With this in mind, Ace Neuroscience offers comprehensive services to develop stroke drug studies targeting different cell types. Based on different drug screening platforms, we screen different cellular synapses, receptors, or targets for active sites of action, and also perform drug screening of different sites for drug candidates with potential stroke activity.

Stroke Drug Development Targeting Other Components

Stroke Drug Development Targeting Other Components

Ace Neuroscience offers comprehensive services to address the role of other factors in the development of stroke drugs. With our professional equipment, advanced technology, and proven service processes, we can ensure the smooth conduct of your study.

Ace Neuroscience is a preclinical CRO biotechnology company focused on the stroke field. We have decades of research experience in the stroke field.

  • We have established different methods of constructing animal models for the stroke drug development research process. Therefore, we provide you with appropriate stroke animal models for different drug development approaches.
  • For drug efficacy testing, pharmacokinetic testing, safety evaluation testing, and pharmaceutic preparation, we also offer specialized services for comprehensive preclinical evaluation of drug candidates.

Our services are flexible and can be tailored to your research and needs. If you would like to learn more about our services, please feel free to contact us.

All of our services are intended for preclinical research use only and cannot be used to diagnose, treat or manage patients.
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